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Dr. Stephen E.P. Smith is a principal investigator at the Norcliffe Foundation Center for Integrative Brain Research and an assistant professor at the University of Washington School of Medicine. He received a PhD from Caltech, where he trained under Dr. Paul Patterson and received funding support from Autism Speaks. Smith completed postdoctoral training at Harvard Medical School and the Mayo Clinic. Dr. Smith's work is focused on the premise that proteins do not act in isolation, but form networks of multi-protein complexes, tiny molecular machines that function only when assembled correctly and working in concert. The SEPS lab develops novel experimental and computational methods to analyze the behavior of these multi-protein complexes. The lab uses these techniques, along with molecular and genetic approaches, to model dynamic protein interaction networks as they process information; to investigate how these networks are disrupted in complex diseases such as autism; and to manipulate these networks to control cellular behavior.
Hosted by Karen Zito ([email protected])